Brain Disorders Library

40-condition encyclopedia with clinical neurology, BrainFacts, NeuroWiki, Riisfeldt, AAN, and PubMed sources — every entry fully illustrated.

Major Depressive Disorder
Mood

Major Depressive Disorder

Involves dysregulation of serotonin, norepinephrine, and dopamine systems. Reduced hippocampal volume and prefrontal cortex activity.

2 videos · 6 sources
Generalized Anxiety Disorder
Anxiety

Generalized Anxiety Disorder

Amygdala hyperactivity, reduced prefrontal regulation, GABA system dysregulation, elevated cortisol.

2 videos · 6 sources
Attention Deficit Hyperactivity Disorder
Neurodevelopmental

Attention Deficit Hyperactivity Disorder

Dopamine and norepinephrine dysregulation. Reduced prefrontal cortex volume and activity. Delayed cortical maturation.

2 videos · 6 sources
Autism Spectrum Disorder
Neurodevelopmental

Autism Spectrum Disorder

Altered connectivity patterns, enlarged brain volume in early development, mirror neuron system differences.

2 videos · 6 sources
Post-Traumatic Stress Disorder
Trauma

Post-Traumatic Stress Disorder

Amygdala hyperactivity, hippocampal volume reduction, prefrontal cortex hypoactivity, HPA axis dysregulation.

2 videos · 6 sources
Schizophrenia
Psychotic

Schizophrenia

Dopamine hypothesis, glutamate dysfunction, reduced gray matter, disrupted connectivity, enlarged ventricles.

2 videos · 6 sources
Bipolar Disorder
Mood

Bipolar Disorder

Circadian rhythm disruption, dopamine dysregulation, white matter abnormalities, altered limbic-prefrontal connectivity.

2 videos · 6 sources
Obsessive-Compulsive Disorder
Anxiety

Obsessive-Compulsive Disorder

Hyperactivity in cortico-striato-thalamo-cortical circuits. Serotonin system involvement. Basal ganglia dysfunction.

2 videos · 6 sources
Alzheimer's Disease
Neurodegenerative

Alzheimer's Disease

Amyloid plaques, neurofibrillary tangles, synaptic loss, hippocampal atrophy, cortical thinning.

2 videos · 6 sources
Parkinson's Disease
Neurodegenerative

Parkinson's Disease

Loss of dopaminergic neurons in substantia nigra. Lewy body formation. Alpha-synuclein aggregation.

2 videos · 6 sources