Great Minds
beginnermolecular neurosciencehistorypioneer

Eric Kandel

Nobel laureate who revealed the molecular mechanisms of memory using the sea slug Aplysia. Showed how learning produces lasting changes in synaptic strength.

Eric Kandel

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Eric Kandel used the sea slug Aplysia to reveal the molecular mechanisms of memory. He showed that short-term memory involves covalent modification of existing proteins, while long-term memory requires new protein synthesis and gene expression — particularly CREB-mediated transcription. Kandel shared the 2000 Nobel Prize and authored 'Principles of Neural Science', the field's definitive textbook.

We are who we are because of what we learn and what we remember.

1929Present · American

Key Discoveries

Molecular basis of memory
CREB and memory consolidation
Synaptic tagging
Aplysia learning circuits

Gallery

Synaptic plasticity

Synaptic plasticity

Memory circuits

Memory circuits

Aplysia neuron

Aplysia neuron

Videos

Nobel Prize — Molecular Memory

Nobel Prize

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2-Minute Neuroscience: LTP

Neuroscientifically Challenged

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